PeptideDB

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)

CAS: 89430-34-2 F: C58H77N13O10 W: 1116.31

Substance P (4-11) is a potent neurokinin NK1 antagonist.Substance P (4-11) inhibits the effects of gold-protein-substan
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Bioactivity [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP)[1].
Invitro [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) (100 nM) dose not exert a direct relaxant or contractile effect, but significantly reduces the vasodilatation induced by SP and GPSP[1].
Name [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)
CAS 89430-34-2
Shortening pQQWFWL-Nle-NH2
Formula C58H77N13O10
Molar Mass 1116.31
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.